Results
HR-HPV infection was present in 14.1% of the study participants. The characteristics of these participants are presented in Table 1 according to either the presence or absence of HR-HPV infection. No significant differences in age, BMI, parity, and number of abortion were observed between women with HR-HPV infection and those without HR-HPV infection. There were no differences in gestational age at delivery or in birth weight between the two groups. Distributions of delivery mode also did not vary substantially between the two groups.
Table 2 shows the prevalence of adverse pregnancy outcomes based on the presence or absence of HR-HPV infection. PROM was more common in patients with HR-HPV infection than in women without HR-HPV. However, the prevalence of preterm delivery, preeclampsia, and GDM was similar between the two groups.
Figure 1 shows the prevalence of HR-HPV infection according to age group. HR-HPV infection was more common in women below the age of 25.
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Figure 1.
Prevalence of high risk-human papillomavirus infection according to age group.
A multivariate logistic regression analysis was used to evaluate the relationship of PROM with HR-HPV infection (Table 3). After controlling for age, parity, number of abortions, BMI, gestational age at delivery, history of preterm birth, and history of PROM, we found that women with HR-HPV infection had an increased risk of PROM (odds ratio, 2.318; 95% confidence interval, 1.079–4.980), when compared with those without HR-HPV infection.