Definition

• Proton pump Inhibitors, also called PPIs, help to stop the enzyme that's producing acid within the wall of the stomach. Gastroesophageal reflux disease (GERD) is a condition in which the stomach contents back up into the esophagus.
  
  

Ingestion

• PPIs are taken before eating. They get to work on the stomach before food is ingested. Usually one pill a day (before breakfast) is enough, but if it doesn't stop the reflux, a proton pump inhibitor can be taken again before dinner.
  
  

Acid Reduction

• It is the acid within the stomach contents that causes the most problems with GERD. By stopping the production of acid, proton pump inhibitors can stop reflux.
  
  

Healing

• PPIs allow for the esophagus to heal. When the damage created by reflux heals, it inhibits additional GERD.
  
  

Preventative

• Long term use of proton pump inhibitors can stop reflux from returning by keeping the esophagus acid-free.